Van de Ven Double Ends Everton's Unbeaten Streak at New Home Ground
Micky van de Ven became the first defender to score two goals in a English top-flight match for Tottenham since Jan Vertonghen in March 2013.
Match summary
The Spurs defender heads into the net twice in first half
Everton's Jake O'Brien has goal disallowed after video check
Pape Matar Sarr nets third in dying moments
This loss is Everton's initial at their new ground
Micky van de Ven found the net twice as Spurs extended their unbeaten run in away games in the Premier League and handed Everton their initial loss at Hill Dickinson Stadium.
The Toffees were undefeated in their five previous fixtures at their new ground at the dockside location, having departed their historic home behind after more than a century at the end of last season.
But Spurs captain the Dutchman pounced on two occasions from corners in the first half to place their strong form at risk, and they were failed to mount a comeback before Pape Matar Sarr - assisted by ex-Everton forward Richarlison - headed home a final goal to seal the victory.
Jake O'Brien believed he had equalized the scores a short while after the defender's opener, directing a powerful header past the Spurs keeper from an Everton corner.
The Portuguese striker, in the meantime, missed a handful of chances, while Vicario made a series of fine stops to ensure Tottenham went five matches on the road without defeat in the English top flight.
But the VAR intervened, advising Craig Pawson to review the goal on the screen and the referee decided that Jack Grealish and the attacker were in an illegal position and had interfered with the Spurs keeper.
This victory moves the manager's side into third place in the Premier League, five points off north London rivals and table-toppers the Gunners.
Everton remain in 14th position and are six points clear of the relegation zone.
Tottenham analysis: Van de Ven excels in duties at each end of the field
Following a uninspiring weekday performance in the European competition against Monaco, where they managed a only two shots on goal, Frank opted for Randal Kolo Muani in attack instead of ex-Everton forward Richarlison.
The new arrival was unable to influence the game before being replaced for the substitute after 60 minutes on the pitch, but it turns out he wasn't needed in the end.
Defender the Dutchman transformed into an attacking force to be reckoned with.
Tottenham's opening strike came from a cleverly executed corner routine, with Rodrigo Bentancur heading the ball toward the six-yard box for an unmarked the defender to head home.
And Ven de Ven - filling in as skipper in the Argentine's unavailability - added his second in first-half stoppage time as he outjumped the England keeper to nod in.
Van de Ven was equally impressive in defence, partnering effectively with his defensive colleague as the pair handled excellently with the numerous deliveries thrown their way by Everton.
Everton analysis: Everton missing finishing touch
Everton's new home had been a happy hunting ground, but it seems the freshness may have faded slightly and supporters headed to the gates after the midfielder's third for Tottenham.
The break in Everton's unbeaten home run will not be a major concern for the manager, but their attacking woes will be.
The forward and the other striker - the Toffees' two established strikers - had scored only a single goal between them before Sunday's outing.
And they were failed to add to that poor tally on a damp and dreary evening on Merseyside.
Beto's performance was summed up when he opted to bicycle-kick a clear chance from close range, despite having space and time to reposition for a simpler attempt that would have challenged Vicario.
Barry, too, failed to influence the game after coming on for the starter in the 65th minute.
It was not for a shortage of opportunity. The majority of the home side's attacks came through the winger and the forward, who tirelessly whipped threatening crosses into the Tottenham box.
What next for these two sides?
The Toffees: Moyes' men head to Sunderland in the Premier League on early November at 20:00 GMT.
Tottenham: The London club travel to Newcastle's ground on late October for their fourth-round League Cup match against Newcastle.